![]() ![]() Your doctor will diagnose the condition by ruling out other possibilities. 1998 339:792-798.No single test can confirm a serotonin syndrome diagnosis. A comparison of four treatments for generalized status epilepticus. Veterans Affairs Status Epilepticus Cooperative Study Group. Sinha S, Naritoku DK: Intravenous valproate is well tolerated in unstable patients with status epilepticus. RAMPART (Rapid Anticonvulsant Medication Prior to Arrival Trial): A double-blind randomized clinical trial of the efficacy of IM midazolam versus IV lorazepam in the pre-hospital treatment of status epilepticus by paramedics. Silbergleit R, Lowenstein D, Durkalski V, et al NETT Investigators. New management strategies in the treatment of status epilepticus. Goldfrank’s Toxicologic Emergencies, 10 th ed. In: Hoffman RS, Howland MA, Lewin NA, et al. Lorazepam vs diazepam for pediatric status epilepticus: a randomized clinical trial. PMID: 11903460Ĭhamberlain JM, Okada P, Holsti M, et al Pediatric Emergency Care Applied Research Network (PECARN). Treatment of refractory status epilepticus with pentobarbital, propofol, or midazolam: a systematic review. PMID: 11547716Ĭlaassen J, Hirsch LJ, Emerson RG, Mayer SA. A comparison of lorazepam, diazepam, and placebo for the treatment of out-of-hospital status epilepticus. It should only be used if the patient is continuously clinically monitored.Īlldredge BK, Gelb AM, Isaacs SM, et al. Supplemental oxygen may mask objective signs of hypoventilation.Arterial blood gas (ABG) analysis is indicated if such monitoring if not available or the EtCO 2 readings are not consistent with the clinical findings. End-tidal CO 2 (EtCO 2 ) monitoring should be used if available but may not be entirely reliable.All patients should receive continuous cardiac and respiratory monitoring, including pulse oximetry.Special attention should be paid to airway positioning as oropharynx tissue relaxation after benzodiazepine administration can often lead to airway obstruction.Sedative/anticonvulsant with few drug-drug interactions. ![]()
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